等待开盘 09-18 09:30:00 美东时间
-0.025
-4.13%
PALI-2108 demonstrated favorable safety, with no serious adverse events, lab abnormalities, or EKG concernsPhase 1b data demonstrated 100% clinical response and promising signals regarding the efficacy of PALI-2108 in
09-17 21:05
Palisades Goldcorp Ltd. ( ($TSE:PALI) ) has provided an announcement. Palisades...
09-10 10:07
First dual-acting anti-inflammatory and anti-fibrotic candidate in development for FSCD, a condition with no approved therapiesPatient dosing expected to commence in H2 2025; Topline data anticipated in Q1 2026Continued
09-05 20:47
Palisade Bio received Health Canada’s No Objection Letter for a Phase 1b clinical study of PALI-2108, a first-in-class, ileocolonic-targeted PDE4 B/D inhibitor for fibrostenotic Crohn’s disease (FSCD). FSCD lacks approved anti-fibrotic therapies, with current treatments addressing symptoms rather than the disease process. The open-label study will enroll 6-12 patients to assess safety, pharmacokinetics, pharmacodynamics, and exploratory endpoints...
09-05 12:45
Palisade Bio announced the release of a Virtual Investor KOL Connect segment featuring Dr. Brian Feagan, a leading expert in Fibrostenotic Crohn's Disease (FSCD) and Inflammatory Bowel Diseases (IBD). Dr. Feagan discussed the challenges with current FSCD treatments and highlighted the need for more effective therapies addressing both inflammation and fibrosis. He shared insights on PALI-2108, a novel localized approach aiming to reduce class-asso...
08-25 13:00
PALI-2108 demonstrated to be safe and well tolerated with no serious adverse events (SAEs)Extended half-life and local bioactivation support convenient once-daily dosing in ulcerative colitis (UC) and fibrostenotic
08-07 21:16
Palisade Bio announced positive data for their novel drug PALI-2108 in treating ulcerative colitis (UC) and fibrostenotic Crohn’s disease (FSCD). The Phase 1b study showed 100% clinical response in UC patients, with significant reductions in inflammation and improved histology. Additionally, the Phase 1a study demonstrated sustained drug levels in colon tissue, supporting once-daily dosing. The company plans to submit a Phase 2 IND application in...
08-07 13:15
PALI-2108 is the first and only PDE4 inhibitor designed to target terminal ileum and colon for fibrostenotic Crohn's disease (FSCD) and ulcerative colitis (UC), to address significant unmet medical needsInflammatory
07-31 20:46
Palisade Bio announced that the China National Intellectual Property Administration has issued a Notice of Allowance for a patent covering PALI-2108, a novel, locally-activated, terminal ileum and colon-targeted PDE4 B/D inhibitor for fibrostenotic Crohn’s disease and moderate to severe ulcerative colitis. The patent, titled “Gut Microbiota-Activated PDE4 Inhibitor Prodrug,” will cover claims on the composition of matter for PALI-2108 in China wi...
07-31 12:45
Shares of Alphabet Inc. (NASDAQ:GOOGL) (NASDAQ:GOOG) rose sharply in pre-market...
07-24 17:23