等待開盤 10-28 09:30:00 美东时间
+0.081
+0.20%
Aprea Therapeutics identified the recommended Phase 2 dose of 1,100 mg once daily for ATRN-119, an oral ATR inhibitor, in the monotherapy arm of its ABOYA-119 Phase 1/2a study for patients with advanced solid tumors. The company is pausing further enrollment in monotherapy arms to focus on strategic high-value combinations, such as DNA-damaging agents and immune checkpoint inhibitors, based on preclinical data suggesting synergistic anti-tumor ef...
10-15 12:00
Apogee Therapeutics announced that data from the Phase 2 APEX trial of APG777 for moderate-to-severe atopic dermatitis has been accepted for a late-breaker oral presentation at EADV Congress 2025 in Paris. The company will also present multiple posters highlighting APG777’s best-in-class potential and its combination strategy with APG990. APG777 met primary and secondary endpoints in the APEX trial, showing strong efficacy and a favorable tolerab...
09-11 11:30
Apogee Therapeutics reported positive 16-week Phase 2 Part A data for APG777, a potentially best-in-class anti-IL-13 antibody for moderate-to-severe atopic dermatitis (AD). The drug met all primary and key secondary endpoints, demonstrating significant efficacy and reduced injection burden for patients, potentially requiring 2-4 injections per year versus 26 for current treatments. Part B of the APEX trial is on track for a mid-2026 readout, with...
08-11 11:00