已收盤 02-06 16:00:00 美东时间
+0.710
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Antigen spreading was evaluated in a subset of Phase 2 patients to assess the ability of ELI-002 7P to broaden immune responses to personalized tumor neoantigens not present in the targeted immunotherapy87% (13/15) of
2025-12-11 21:04
SITC abstracts highlight updated immunogenicity results from the Phase 2 AMPLIFY-7P trial of ELI-002 7P and preclinical data on the use of intratumoral ELI-004 (AMP-CpG) for solid tumor immunotherapyELI-002 7P induced
2025-11-07 22:10
ELI-002 7P demonstrated robust mKRAS-specific T cell responses across a broad range of HLA types, highlighting its potential for use among a diverse patient populationPatients treated with ELI-002 7P represented a
2025-10-27 20:22
Elicio Therapeutics announced preliminary results from its Phase 2 AMPLIFY-7P trial showing ELI-002 7P induced robust mKRAS-specific T cell responses across a diverse HLA population. Among 89 patients, 1,132 unique HLA types were identified, with 99% of patients (88/89) developing mKRAS-specific T cell responses. These findings suggest ELI-002 7P may benefit a broad spectrum of pancreatic ductal adenocarcinoma (PDAC) patients, addressing a critic...
2025-10-27 12:00
Study will evaluate ELI-002 7P in combination with chemotherapy and a checkpoint inhibitor ("CPI") in the neoadjuvant setting Trial is anticipated to begin enrolling in H1'2026 BOSTON, Sept. 29, 2025 (GLOBE
2025-09-29 20:19
Elicio Therapeutics plans to initiate a Phase 1 neoadjuvant study of ELI-002 7P, an investigational AMP cancer vaccine targeting KRAS-driven cancers, in combination with chemotherapy (mFOLFIRINOX) and an anti-PD-1 checkpoint inhibitor for pancreatic ductal adenocarcinoma (PDAC). The investigator-initiated trial, led by Dr. Kevin Soares of Memorial Sloan Kettering Cancer Center and funded by the Lustgarten Foundation, aims to enroll 20 patients ac...
2025-09-29 12:00
Elicio Therapeutics granted 9,800 inducement stock options to two new employees on September 15, 2025, priced at $10.08 per share, vesting over four years. The company, focusing on novel immunotherapies for high-prevalence cancers, is advancing its lead program ELI-002, an off-the-shelf vaccine targeting KRAS mutations, with promising data from Phase 1 studies in pancreatic and colorectal cancers. Elicio plans to expand ELI-002 to other indicatio...
2025-09-18 12:00
ELI-002 induced mKRAS-specific T cell responses in 99% of evaluable patients (89 of 90) who were treated with the investigational vaccine immunotherapyRobust mKRAS-specific T cell responses were observed with an average
2025-09-17 20:08
迅雷绩后上演翻倍行情!投资影石创新浮盈超50亿;OpenDoor隔夜大涨19%,此前获知名加密货币投资者买入>>
2025-08-19 19:53
Elicio Therapeutics reported promising results from the Phase 1 AMPLIFY-201 study of ELI-002, a mutant KRAS (mKRAS)-targeting vaccine, in patients with pancreatic and colorectal cancers. The study showed a significant improvement in overall survival (OS) from 16.33 to 28.94 months, alongside a 77% reduction in the risk of death and an 88% reduction in the risk of relapse. ELI-002 induced robust T cell responses, particularly CD4+ and CD8+ mKRAS-s...
2025-08-12 12:00