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Genentech多发性硬化症候选药物非奈替尼在后期试验中达到目标

2026-02-08 06:15

  • Roche (RHHBY)-owned Genentech said that its multiple sclerosis asset fenebrutinib met its primary endpoint in a phase 3 trial.
  • Fenebrutinib reduced the risk of disability progression by 12% compared to Ocrevus (ocrelizumab) as soon as 24 weeks in individuals with primary progressive multiple sclerosis. 
  • Genentech noted that clinical improvement was particularly notable in upper limb function.
  • Fenebrutinib, a Bruton’s tyrosine kinase (BTK) inhibitor, has a significant benefit over Ocrevus in that it is given as a pill.
  • The candidate is also in two other phase 3 trials for relapsing multiple sclerosis.

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