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吉利德行使大会生物科学疱疹项目许可证

2025-12-23 00:42

  • Gilead Sciences (GILD) has exercised an option to license Assembly Biosciences (ASMB) herpes simplex virus helicase-primase inhibitor programs for recurrent genital herpes.
  • The deal covers phase 1 oral candidates ABI-1179 and ABI-5366. Both inhibit the enzyme viral helicase-primase, which is necessary for herpes virus replication.
  • The two companies signed an agreement in October 2023 for a 12-year partnership to research and develop novel antiviral therapies. Assembly received an $84.8M upfront payment and a $15.2M equity investment from Gilead, which also agreed to buy ~30% of Assembly Bio stock. In addition, Assembly is eligible for ~$330M in milestone payments per program. 

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