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葛兰素史克结束与IDEAYA就两名候选人进行合作

2025-12-06 06:04

  • GSK (GSK) is terminating a collaboration and licensing agreement with IDEAYA Biosciences (IDYA) for two of the latter's assets.
  • The 2020 pact covers the Werner Helicase (IDE275) and Pol Theta (IDE705) clinical programs, both under investigation to treat solid tumors.
  • The two programs utilize synthetic lethality, a relatively new field in oncology treatments involving genetic interaction where the combination of two genetic events results in cell death or death of an organism.
  • The agreement called for IDEAYA to receive US profit share and ex-US royalties for both candidates. IDEAYA also received a $100M upfront payment. 

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