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Altimune发布MASH额外2期培维杜肽数据

2025-11-11 23:04

  • Additional data from the phase 2b trial of Altimmune's (ALT) pemvidutide for metabolic dysfunction-associated steatohepatitis (MASH) some improvements in the liver condition over 24 weeks of treatment.
  • The trial has two primary endpoints, MASH resolution without worsening of fibrosis and fibrosis improvement without worsening of MASH. For the first endpoint, the figures were, respectively, 58% and 52%, for the 1.2 mg and 1.8 mg (20% placebo) doses, and 33% and 36% for the second (28% placebo). 
  • The latest information follows topline results of the dual glucagon and GLP-1 receptor agonist released in June 2025. However, the company's shares dropped precipitously then as the Street viewed the results as mixed. 

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