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Ideaya Biosciences报告了Darovasertib联合辉瑞克唑替尼1X治疗转移性葡萄膜黑色素瘤的I/II期试验(OptimUM-01)的中位总生存期结果

2025-10-20 18:12

  • Combination demonstrated median overall survival (OS) of 21.1 months, compared to reported historical mOS of approximately 12 months in published meta-analysis of metastatic uveal melanoma in the first-line setting
  • Median progression free survival (PFS) of 7.0 months
  • Confirmed overall response rate (ORR) by RECIST 1.1 of 34%, median duration of response (mDOR) of 9 months and disease control rate (DCR) of 90%

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