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Skye在Evercore因肥胖资产nimacimab而发起超重

2025-08-15 21:43

  • Evercore ISI is bullish on the prospects for Skye Bioscience (NASDAQ:SKYE) due to its development of the CB1 inhibitor nimacimab for obesity.
  • The firm has a $10 price target (~206% upside based on Thursday's close).
  • Analyst Michael DiFiore believes that as a CB1 inhibitor, nimacimab would differentiate itself from the GLP-1s from Novo Nordisk (NVO) and Eli Lilly (LLY) that are dominating the market.
  • He noted that the candidate could fill gaps in obesity care in several ways: as a GLP-1 off-ramp/maintenance option; as a combo therapy in severe obesity; and as a non-incretin monotherapy for some patients.
  • DiFiore added that the newest generation of CB1 inhibitors appears to avoid the central nervous issues that plagued earlier generations. 
  • Looking ahead, he sees the next major catalyst for nimacimab coming in late Q3 or early Q4 with phase 2a data.

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