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Ironwood因与不良相关的挑战而在杰富瑞降级

2025-04-16 00:10

  • Ironwood Pharmaceuticals (NASDAQ:IRWD) has been downgraded to Hold from Buy at Jefferies after the company announced pressures related to its lead asset, apraglutide. 
  • The company announced Monday that it has decided to evaluate strategic alternatives after the FDA required an additional Phase 3 trial to secure approval for its apraglutide.
  • The downgrade by Jefferies reflects increased uncertainty around the drug’s development timeline and approval prospects, with analysts saying that while they previously viewed apraglutide’s clinical profile as a strength, the need for another pivotal study introduces a delay in potential approval, now expected no earlier than 2029, and adds regulatory and financial uncertainty. 
  • Jefferies has lowered its PT to $0.70 from $8 per share.

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