Immunovant的3期Batoclimab研究均未能达到甲状腺眼部疾病的主要前凸反应率终点

2026-04-02 17:08

Phase 3 studies of batoclimab in thyroid eye disease (TED) each failed to meet their primary endpoint; safety results were consistent with previous findings
Patients in the TED studies demonstrated greater levels of proptosis improvement from baseline after the initial 12-week high-dose period than after the following 12-week low-dose period, supporting the benefit of deeper IgG suppression. The hyperthyroid patients in the TED studies showed similar response rates of thyroid hormone normalization to those seen in the batoclimab Phase 2 study in Graves' disease
Immunovant remains focused on rapid advancement of IMVT-1402 in multiple indications