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眼部疾病药物第二阶段失败后,KALA比奥股价暴跌92%

2025-09-29 20:56

  • Shares of KALA Bio (BIO) have plummeted ~92% in premarket trading Monday after reporting that a phase 2 trial of its persistent corneal epithelial defect (PCED) candidate KPI-012 missed its key goal.
  • Besides missing the primary endpoint of complete healing of PCED as measured by corneal fluorescein staining, the CHASE trial also missed on secondary efficacy endpoints.
  • As a result, KALA will end development of KPI-012 -- which was its lead product -- along with its mesenchymal stem cell secretome (MSC-S) platform.
  • Also, the company will evaluate strategic options and preserve cash, including cutting staff.

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