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Corcept Therapeutics在欧洲ALS治疗网络2025年年会上展示了Dazucorilant在ALS患者中的DAZALS研究结果,DAZALS未达到其主要终点,即与安慰剂相比,ALS功能评定量表修订版的结局改善

2025-06-05 18:08

  • DAZALS did not meet its primary endpoint of improved outcome in the ALS Functional Rating Scale-Revised (ALSFRS-R) in patients who received dazucorilant compared to patients who received placebo
  • DAZALS met its secondary endpoint of improved overall survival at week 24 of the study in patients who received 300 mg of dazucorilant compared to patients who received placebo
  • Exploratory analysis at the one-year mark shows continued significant improvement in overall survival between patients who received 300 mg of dazucorilant and those who received placebo only
  • Corcept seeking guidance from United States and European regulators on optimum path forward

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