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强生将癫痫病候选人交给Addex,结束长达数十年的合作伙伴关系

2025-04-18 01:30

  • Swiss biopharma Addex Therapeutics (NASDAQ:ADXN) announced Thursday that Johnson & Johnson (NYSE:JNJ) has returned all development and commercialization rights linked to its epilepsy candidate ADX71149, ending a more than 20-year-long partnership between the two firms.
  • J&J’s decision comes nearly nine months after the company decided to discontinue the development of ADX71149 (JNJ-40411813) in epilepsy following a mid-stage trial setback for the small molecule therapy. 
  • The positive allosteric modulator (PAM) of metabotropic glutamate receptor-2 was developed as part of a collaboration between the Geneva-based company and J&J’s Janssen unit, launched in 2004.
  • “ADX71149 is a high-quality asset which has completed three Phase 2 studies, so we are excited to regain control of its development from our partner with its high-quality data package and significant material,” CEO Tim Dyer said.

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