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Replimune在黑色素瘤中的RP 1组合结果增加了30%

2024-06-07 00:05

  • Replimune Group (NASDAQ:REPL) said that topline results of an analysis of a trial of RP1 plus Bristol-Myers Squibb's (BMY) Opdivo (nivolumab) in melanoma patients who failed on a PD-1 inhibitor indicated one-third of them responded to the combination treatment.
  • Patients enrolled in the IGNYTE trial had progressed while on a PD-1 inhibitor for at least 8 weeks.
  • Results also showed durability with all responses lasting more than six months and median duration of response of more than 35 months.
  • Replimune is up ~30% in early Thursday afternoon trading.
  • The company plans to submit a Biologics License Application to the U.S. FDA in the second half of the year and enroll the first patients in the IGNITE-3 confirmatory trial in Q3.

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